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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
25.76
Human Site:
S259
Identified Species:
51.52
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
S259
S
V
C
G
W
A
C
S
S
S
L
E
S
M
Q
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
S259
S
V
C
G
W
A
C
S
S
S
L
E
S
M
Q
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
S259
S
V
C
G
W
A
C
S
S
S
L
E
P
M
Q
Dog
Lupus familis
XP_532428
589
65257
S346
S
V
C
G
W
A
C
S
S
S
L
E
P
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
S259
S
L
C
G
W
A
C
S
S
L
E
P
T
Q
L
Rat
Rattus norvegicus
NP_001120765
501
55306
S259
S
L
C
G
W
A
C
S
S
L
E
P
T
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
S318
A
V
F
G
W
A
C
S
S
S
S
E
S
T
H
Chicken
Gallus gallus
XP_414975
484
53210
V243
Q
V
H
I
P
A
C
V
L
A
L
C
G
W
T
Frog
Xenopus laevis
Q6P7H4
477
53273
Q237
S
L
P
S
D
S
L
Q
V
H
I
S
A
C
I
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
S250
A
L
C
G
W
A
A
S
P
S
L
H
A
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
E62
S
W
F
A
K
P
D
E
V
S
P
L
R
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
G296
L
P
Y
A
V
D
C
G
T
E
F
H
S
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
100
93.3
93.3
N.A.
53.3
53.3
N.A.
66.6
26.6
6.6
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
66.6
66.6
N.A.
73.3
33.3
33.3
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
0
75
9
0
0
9
0
0
17
0
17
% A
% Cys:
0
0
59
0
0
0
75
0
0
0
0
9
0
17
0
% C
% Asp:
0
0
0
0
9
9
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
17
42
0
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
67
0
0
0
9
0
0
0
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
9
0
17
0
0
9
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
34
0
0
0
0
9
0
9
17
50
9
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
9
0
9
9
0
0
9
0
9
17
17
0
0
% P
% Gln:
9
0
0
0
0
0
0
9
0
0
0
0
0
17
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
67
0
0
9
0
9
0
67
59
59
9
9
34
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
17
9
9
% T
% Val:
0
50
0
0
9
0
0
9
17
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
67
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _